DNK-metiltransferaza (citozin-N4-specifična)
| DNK-metiltransferaza (citozin-N4-specifična) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.113 | ||||||||
| CAS broj | 169592-50-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
DNK-metiltransferaza (citozin-N4-specifična) (EC 2.1.1.113, modifikaciona metilaza, restrikciono-modifikacioni sistem, DNK(citozin-N4)metiltransferaza, Mtase (formira m4C), S-adenozil-L-metionin:DNK-citozin 4-N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:DNK-citozin N4-metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovao je velika grupa enzima, većina kojih ima sličnu specifičnost sa enzimima grupa EC 3.1.21.3, EC 3.1.21.4 i EC 3.1.21.5.
Reference
[уреди | уреди извор]- ^ Kessler, C. & Manta, V. (1990). „Specificity of restriction endonucleases and DNA modification methyltransferases: a review”. Gene. 92: 1—248. PMID 2172084.
- ^ Klimasauskas, S., Timinskas, A., Menkevicius, S., Butkiene, D., Butkus, V. and Janulaitis, A. (1989). „Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases”. Nucleic Acids Res. 17: 9823—9832. PMID 2690010.
- ^ Roberts, R.J. (1990). „Restriction enzymes and their isoschizomers”. Nucleic Acids Res. 18: 2331—2365. PMID 2159140.
- ^ Yuan, R. (1981). „Structure and mechanism of multifunctional restriction endonucleases”. Annu. Rev. Biochem. 50: 285—319. PMID 6267988.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Site-specific+DNA-methyltransferase+(cytosine-N4-specific) на US National Library of Medicine Medical Subject Headings (MeSH)
